Ovarian cancer

-  A leading cause of death among women with gynecologic malignancies

- Average lifetime risk for women in US is 1 in 70.

- Epithelial ovarian cancers account for 90% of all ovarian malignancies

- Standard therapy for advanced ovarian cancer following cytoreductive surgery, is platinum-based chemotherapy.

Chronic fatigue

I was trying to understand how does chronic diseases like cancer, some viral infections, MS and even drugs like the B-blockers cause fatigue. It is interesting that very little seems to be known about this very common phenomenon.There are a few proposed mechanisms for cancer-related fatigue including:

- proinflammatory cytokine hypothesis
-growth factors hypothesis
- circadian rhythm modulation hypothesis
- HPA axis disruption hypothesis
- serotonin dysregulation hypothesis
- vagal-afferent-activation hypothesis
- anemia hypothesis
- generation/use of ATP hypothesis

New blog

Welcome to this blog. I plan to blog about medical stuff in this blog. Probably from a perspective of a Malaysian-trained doctor who happens to be passing some time in Australia. Not so much intended for the general public or for senior doctors. Medical students and junior doctors are probably my main target. Let's begin this journey...